Human chromosome 21 gene function and pathway database
with knowledge discovery tools

Protein Protein Interactions & Gene Structure Information & Pathways

  • Search by chromosome 21 or orthologous mouse gene name, accession number
  • Obtain gene structures of alternative splice variants and their protein parameters; graphical representations of protein interactions (primary, secondary, tertiary, etc) of orthologues in model organisms; pathway visualization.
  • Warning: you need to change the Java Runtime parameters, please click here to see instruction.
  • This application is designed for best use with Internet Explorer.
  • Genes structure & protein information Displays exon, intron, UTR structure of the genes annotated by the project. After you have entered some input, for example, a gene name, a list will pop up. You need to highlight row of interest and hit Enter to see the results.

    Protein interactions Display protein protein interaction network, predict protein function based on interaction network

    Protein Interaction Paths Search all available paths between two proteins

    Chr21 Protein Interaction Paths Search all shortest paths between a Chr21 protein to other Chr21 proteins

    HPRD proteins vs Chr21 Proteins Display all HPRD protein interaction connected with Chr21 proteins

    Ortholog Protein interactionsDisplay ortholog protein protein interaction network

    Protein Interaction In Other OrganismDisplay protein protein interaction network in other organisms and marked the proteins which have orthologs in chr21
    Protein Interaction InteractionDisplay protein protein interaction network in which chr21 proteins are highlighted
    Pathway VisualizationDisplay pathway network in which chr21 proteins are highlighted